Description
Product Characteristics:
Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).
Subcellular location: Cell membrane
Synonyms: CD99B, MIC2L1, CD99 antigen-like protein 2, MIC2-like protein 1, CD99, CD99L2, UNQ1964/PRO4486
Target Information: This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]